Moon-shot: Develop total artificial heart.
Immediate: Promote bioengineering research in Engineering Institutes of India in collaboration with Medical Institutions, Engineering Industries and Medical device developers.
SHARE INDIA, Hyderabad, India
Chaitanya Bharathi Institute of Technology (CBIT), Hyderabad, India
Kakatiya Institute of Technology & Science, (KITS) Warangal, India
Sree Nidhi Institute of Science and Technology (SNIST), Hyderabad, India
Asian Institute of Gastroenterology, Hyderabad, India
Laxven Industries, Hyderabad, India
Palamur Biosciences Pvt. Ltd., Mahbubnagar, India
Shree Pacetronix Ltd., Indore, India
University of Pittsburgh, Pittsburgh, USA
Cornell Engineering, Cornell University, Ithaca, New York, USA
Inspired Therapeutics, Florida, USA
University of Pennsylvania, Pennsylvania, USA
enmodes GmbH, Aschen, Germany
Kaarthik Moulds & Dies, Hyderabad
Funding source: Self-funding by Indian Institutions aided by SHARE INDIA and SHARE USA
Development Approach of the Project
M/s. Laxven Systems is developing Centrifugal Levitation Pump for extracorporeal LVAD and CBIT is developing Centrifugal Pump with magnetically coupled impellor and Pivot bearing. KITS also entered into the scene recently and is working on Centrifugal Pump. SNIST is working on fabrication of Centrifugal Pump impellor and housing by Injection molding. SNIST is also working on Axial Levitation Pump for implant.
Status of the Project
Protocol for blood pump suitable for bench testing and pre-clinical readiness was finalized with the help of Dr. Salim Olia and Prof. Harvey Borovetz. Laxven Systems is working on a pump with rotating disk operating under the “maglev” principle which is suspended in its casing via magnetic levitation. CBIT and KITS will use the Maglev motor to develop a Centrifugal Levitation Pump with magnetically coupled impellor and pivot bearing.
Magnetic coupled blood pump P28 Prototype was 3D printed and tested using Mock loop bench testing setup with animal blood at AIG Hospital. The experiment was successfully conducted with human blood according to the ASTM 1830-19 standard for in vitro Evaluation of Hemolysis in Blood Pumps
Drawings for CENTRIMAG pump are also generated with the help of DRDO. Titanium material, which is bio compatible was received from DRDO on special request. Impeller was made by precision machining on 4 axis machining centre at Kaarthik Moulds & Dies, Hyderabad. The pump housing and impeller will be 3D printed with poly carbonate at CBIT.
Palamur Biosciences (PBS) GLP animal testing facility for Pre-clinical cardiac devices testing was added as a valuable partner. The facility is equipped with state-of-the-art CathLab facility, IVUS, 4DECHO, Heart Lung Machine, animal housing facilities and OT.
PBS, CBIT and AIG successfully conducted pre-clinical investigations on effects of implantation of arterial and venous cannulae and testing arterio-venous blood flow using external ECMO pump in sheep with online support from the USA collaborators.