TB study

TB study

(A) Indian Council of Medical Research (ICMR) funded National Tuberculosis Elimination Programs (NTEP) Projects:

1. Improving TB diagnosis at Designated Microscopic Centers (DMCs) by introduction of Quality Management Systems (QMS) and optimum utilization of rapid molecular diagnostics and its cost implications; Principal Investigator: Dr. Shikha Dhawan, Director Programs, SHARE INDIA Brief Description: We propose incremental yields in establishment of QMS at DMCs under NTEP that will also positively impact utilization of rapid molecular diagnostics like TrueNat and CBNAAT for diagnosis of TB and Rifampicin resistance. Through this study, we want to establish models of laboratory-driven quality improvement like periodic machine calibrations, reducing test errors, preventing stock-outs, improving supply chain etc to enhance performance and utilization of newly established TrueNat and previously deployed CBNAAT systems under NTEP’s DMCs with evidence of patient impact.

2. TB prevalence and interventions for reducing TB and LTBI in high risk key population of rickshaw drivers and construction work; Principal Investigator: Dr. Shikha Dhawan, Director Programs, SHARE INDIA
Brief Description: We provide evidence for TB prevalence in rickshaw drivers in Delhi and construction workers in Bangalore Urban. We expand spectrum for TB case finding and interventions for latent TB infection (LTBI) in these high risk groups. We not just link these key populations to NTEP facilities for diagnosis and treatment; we also find and link their co-workers and contacts including school children and children’s household contacts in the true spirit of “leaving no one behind”. The study will generate evidence to positively influence the national policy for providing TB preventive therapy to rickshaw drivers & construction workers in addition to PLHIV and children. Detecting and treating LTBI among rickshaw drivers & construction workers will have a long term gain in bringing down the annual notification of incident TB by preventing development of new LTBI infections, reduced annual risk for TB infection (ARTI) and curtailing TB transmission.


(B) The Global Fund to Fight AIDS, Tuberculosis and Malaria (GFATM)/ National AIDS Control Organization (NACO) funded Project:

1. Design and develop comprehensive advocacy, communication strategies and tools for National AIDS Control Organization (NACO), Ministry of Health and Family Welfare, Government of India; Principal Investigator: Dr. Shikha Dhawan, Director Programs, SHARE INDIA
Brief Description: The project is designed to develop a new age communication and advocacy strategy to meet 95-95-95 fast track targets by 2025 and provide a way for elimination of HIV/AIDS by 2030. Under the project, community-based behavior change communication tools will be developed to achieve the targets set under the National Strategic Plan. National and State Communication Digital Repository with standardized contents will be maintained and utilized for equitable access. Tools for reach, recall and impact of communication activities will be developed and executed. Strategy will be development for addressing stigma and discrimination related to HIV and effective implementation of the HIV and AIDS (Prevention and Control) Act, 2017. It is proposed to use communication as a tool for improving gains across all program components with an overall aim to support NACO’s IEC and Mainstreaming Division in a 360-degree multimedia approach encompassing advocacy and communication strategies.